According to a new report, taking oral antibiotics at a higher quantity may have some adverse effect.
Taking any five types of oral antibiotics lead to higher risk of developing kidney stones, a new study found. A study published Thursday in the Journal of the American Society of Nephrology. When the deposits of mineral and salt form in the kidneys and must be passed through the urinary tract is called kidney stones. It has grown much more common over the past few decades. This condition is linked to bacterial changes in the intestines and urinary tract. The researchers from The Children’s Hospital of Philadelphia (CHOP) conducted a study to determine the relationship between antibiotics and kidney stones.
The researchers analyzed the records of the health of more than thirteen million people who sought care between 1994 and 2015 in the United Kingdom. They found that about 26,000 patients diagnosed with kidney stones who had antibiotic exposure, compared to a control group nearly 260,000 people without kidney stones.
Sulfas, cephalosporins, fluoroquinolones, nitrofurantoin and broad-spectrum penicillins are the five classes of oral antibiotics which were associated with a kidney stone diagnosis, they found after reviewing the results.
Those people who had received sulfa drugs were more than twice as likely to have kidney stones and those people who had been given penicillins had a 27 percent increased risk of getting them.
The higher risk was found among children. After use of antibiotic, the risk remained elevated years.
Jacob, who an infectious disease specialist at Emory University, said, “People take antibiotics just to be safe, but they don’t think about what some of the downsides are.” Jacob added, “For example, antibiotics can disrupt your gut microbiome. That change of what’s naturally in you can have consequences.” Jacob was not a part of the trial.
Jacob said, “The next time you think you need an antibiotic, ask your doctor, ‘is this an infection that antibiotics are going to help?’ That’s the conversation that needs to happen.”